Transfer RNA Maturation Defects Lead to Inhibition of ribosomal RNA Processing via Synthesis of pppGpp

Aude Trinquier , Jonathan E Ulmer , Laetitia Gilet , Sabine Figaro (1) , Philippe Hammann (2) , Lauriane Kuhn , Frédérique Braun (3) , Ciaran Condon

1 EGM (UMR_8261 / FRE_3630) - Expression Génétique Microbienne
2 Platforme Prote Strasbourg Esplanade
3 CRCNA - Centre de Recherche en Cancérologie Nantes-Angers

Mots clés: tRNA; rRNA; ppGpp; stringent response; ribosome biogenesis; RNA maturation

Domaines: Sciences du Vivant [q-bio]; Biochimie, Biologie Moléculaire; Biologie moléculaire

Aude Trinquier, Jonathan E Ulmer, Laetitia Gilet, Sabine Figaro, Philippe Hammann, et al.. Transfer RNA Maturation Defects Lead to Inhibition of ribosomal RNA Processing via Synthesis of pppGpp. Molecular Cell, 2019, ⟨10.1016/j.molcel.2019.03.030⟩. ⟨hal-02104413⟩