Detection of RHDV strains in the Iberian hare ( Lepus granatensis ): earliest evidence of rabbit lagovirus cross-species infection. - Centre de recherche en cancérologie Nantes-Angers Unité Mixte de Recherche 892 Inserm - 6299 CNRS Accéder directement au contenu
Article Dans Une Revue Veterinary Research Année : 2014

Detection of RHDV strains in the Iberian hare ( Lepus granatensis ): earliest evidence of rabbit lagovirus cross-species infection.

Résumé

: Rabbit hemorrhagic disease virus (RHDV) is a highly lethal Lagovirus, family Caliciviridae, that threatens European rabbits (Oryctolagus cuniculus). Although a related virus severely affects hares, cross-species infection was only recently described for new variant RHDV2 in Cape hares (Lepus capensis). We sequenced two strains from dead Iberian hares (Lepus granatensis) collected in the 1990s in Portugal. Clinical signs were compatible with a Lagovirus infection. Phylogenetic analysis of the complete capsid gene positioned them in the RHDV genogroup that circulated on the Iberian Peninsula at that time. This is the earliest evidence of RHDV affecting a species other than European rabbits.
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Dates et versions

inserm-01072010 , version 1 (07-10-2014)

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Ana M. Lopes, Sara Marques, Eliane Silva, Maria J. Magalhães, Ana Pinheiro, et al.. Detection of RHDV strains in the Iberian hare ( Lepus granatensis ): earliest evidence of rabbit lagovirus cross-species infection.. Veterinary Research, 2014, 45 (1), pp.94. ⟨10.1186/PREACCEPT-2643101671316388⟩. ⟨inserm-01072010⟩
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