CRISTAL-BONSAI collection |
 |
Article dans une revue
Norine: update of the nonribosomal peptide resource
Abstract : Norine, the unique resource dedicated to nonribo-somal peptides (NRPs), is now updated with a new pipeline to automate massive sourcing and enhance annotation. External databases are mined to extract NRPs that are not yet in Norine. To maintain a high data quality, successive filters are applied to automatically validate the NRP annotations and only validated data is inserted in the database. External databases were also used to complete annotations of NRPs already in Norine. Besides, annotation consistency inside Norine and between Norine and external sources have reported annotation errors. Some can be corrected automatically, while others need manual curation. This new approach led to the insertion of 539 new NRPs and the addition or correction of annotations of nearly all Norine entries. Two new tools to analyse the chemical structures of NRPs (rBAN) and to infer a molecular formula from the mass-to-charge ratio of an NRP (Kendrick Formula Predictor) were also integrated. Norine is freely accessible from the following URL: https://bioinfo.cristal.univ-lille.fr/ norine/
Littérature citée [14 références]
https://hal.archives-ouvertes.fr/hal-02376009
Contributeur : Areski Flissi Connectez-vous pour contacter le contributeur
Soumis le : vendredi 22 novembre 2019 - 12:19:44
Dernière modification le : jeudi 7 avril 2022 - 10:10:38
Contributeur : Areski Flissi Connectez-vous pour contacter le contributeur
Soumis le : vendredi 22 novembre 2019 - 12:19:44
Dernière modification le : jeudi 7 avril 2022 - 10:10:38
Fichier
gkz1000.pdf
Fichiers éditeurs autorisés sur une archive ouverte
Licence
Distributed under a Creative Commons Paternité - Pas d'utilisation commerciale 4.0 International License