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Communication Dans Un Congrès Année : 2017

A Performance Comparison between Continuous-Wave and Time-Domain Diffuse Optical Tomography for Deep Inclusions by Using Small Source-Detector Separations

Résumé

Continuous-wave (CW) is the most widely used and commercially available technique for performing biomedical diffuse optics tomography. Nevertheless, CW has been proved to suffer from non-uniqueness problems and large source-detector distances have to be used in order to detect inclusions that are deep from the surface. In order to overcome the former drawback frequency-domain approach has been developed although it also suffers from the latter deficiency. Recently, time domain (TD) diffuse optics has attracted huge interest from the scientific community due to its inherit capacity to associate photons arrival time with the maximum depth that they have reached ; the late arrival photons are the photons that have travelled most and presumably have gone deeper in the tissue. Moreover, not long ago it was proved that in TD there is no need of large source-detector distances for the reconstruction of deep layers of human tissue ; in fact small source-detector separations (s.d.s.) improve the contrast and the absolute number of detected photons. However, no comparison analysis has been done in terms of reconstruction quality when using small s.d.s. In this work finite element method is used to do a computational comparison between CW and TD approaches where special emphasis is put on the quality of reconstructions 1) with an inclusion at deep levels and 2) when using small s.d.s. TD reconstructions were done using Mellin-Laplace (TD-ML) transform which is fast to calculate and stable to noise. For the experiments, synthetic computationally generated data was used which was convolved with a single-photon avalanche diode detector instrumental response function.
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Dates et versions

hal-01520731 , version 1 (12-05-2017)

Identifiants

  • HAL Id : hal-01520731 , version 1

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David Orive-Miguel, Jean-Marc Dinten, Jerome I. Mars, Laurent Condat, Lionel Hervé. A Performance Comparison between Continuous-Wave and Time-Domain Diffuse Optical Tomography for Deep Inclusions by Using Small Source-Detector Separations. JIONC 2017 - 12e Journées Imagerie Optique Non-Conventionnelle, GDR ISIS, GDR ONDES, Club Physique et Imagerie Optique de la SFO, Mar 2017, Paris, France. ⟨hal-01520731⟩
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