Follow-Up of Elevated Blood Lead Levels and Sources in a Cohort of Children in Benin - Département Méthodes quantitatives en santé publique Accéder directement au contenu
Article Dans Une Revue International Journal of Environmental Research and Public Health Année : 2020

Follow-Up of Elevated Blood Lead Levels and Sources in a Cohort of Children in Benin

Romeo Zoumenou
  • Fonction : Auteur
  • PersonId : 1035923
Nadine Fievet
  • Fonction : Auteur
  • PersonId : 918379
Michel Cot
  • Fonction : Auteur
  • PersonId : 1035924

Résumé

Lead exposure is associated with poor cognitive development in children. Very few studies in sub-Saharan Africa (SSA) have studied blood lead levels (BLLs) and non-gasoline sources of exposure in children. Data from a birth cohort in Benin (2011-2013) suggested that 58% of 1-year-old children had BLLs > 50 ug/L. We aimed to investigate the prevalence of elevated BLLs (>50 mu g/L and >100 mu g /L) among 425 of these children at 6 years of age in 2016-2018 and to compare BLLs between age 1 and 6 years, and study sources of lead at age 6 years. BLLs were analysed by inductively coupled plasma mass spectrometry. Multiple linear regression and quantile regressions were used to study potential sources of lead. The prevalence of BLLs > 50 mu g/L in children was 59.5% (Geometric Mean (GM) 56.4 mu g/L, 95% CI: 54.1-58.7) at 6 years of age compared to 54.8% (GM 56.5 mu g/L, 95% CI: 53.4-59.6) at 1 year of age. The prevalence of children with BLLs > 100 mu g/L decreased from 14.4% at 1 year of age to 8.2% at 6 years of age. After adjustment for all other covariates, consumption of peanuts more than once per month was significantly associated with a 22.0% (95% CI: 4.6, 42.5) increment in BLLs at age 6 years compared with no consumption. Consumption of bushmeat killed by lead bullets at age 6 years was associated with an increase in the higher percentiles of BLLs (P75) compared with the absence of this source. Other potential sources of lead associated with BLLs with marginal significance were consumption of rice, paternal occupational exposure, and the presence of activity with the potential use of lead. This prospective cohort confirms the persistently high prevalence of elevated BLLs in children residing in a rural region in the south of Benin, as well as the presence of multiple and continuous sources of lead. These results highlight the need for prevention programs to reduce and eliminate lead exposure in children.
Fichier principal
Vignette du fichier
ijerph-17-08689.pdf (3.54 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03093961 , version 1 (01-02-2021)

Licence

Paternité

Identifiants

Citer

Shukrullah Ahmadi, Barbara Le Bot, Romeo Zoumenou, Severine Durand, Nadine Fievet, et al.. Follow-Up of Elevated Blood Lead Levels and Sources in a Cohort of Children in Benin. International Journal of Environmental Research and Public Health, 2020, 17 (22), ⟨10.3390/ijerph17228689⟩. ⟨hal-03093961⟩
90 Consultations
38 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More