C. Anselme, A. Vallier, S. Balmand, M. Fauvarque, and A. Heddi, Host PGRP Gene Expression and Bacterial Release in Endosymbiosis of the Weevil Sitophilus zeamais, Applied and Environmental Microbiology, vol.72, issue.10, pp.6766-72, 2006.
DOI : 10.1128/AEM.00942-06
URL : https://hal.archives-ouvertes.fr/hal-00391129

I. Barros, B. Divya, I. Martins, F. Vandeperre, R. S. Santos et al., Post-capture immune gene expression studies in the deep-sea hydrothermal vent mussel Bathymodiolus azoricus acclimatized to atmospheric pressure, Fish & Shellfish Immunology, vol.42, issue.1, pp.159-70, 2015.
DOI : 10.1016/j.fsi.2014.10.018

R. Bettencourt, P. Dando, P. Collins, V. Costa, B. Allam et al., Innate immunity in the deep sea hydrothermal vent mussel Bathymodiolus azoricus, Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, vol.152, issue.2, pp.278-89, 2009.
DOI : 10.1016/j.cbpa.2008.10.022

R. Bettencourt, M. Pinheiro, C. Egas, P. Gomes, M. Afonso et al., Highthroughput sequencing and analysis of the gill tissue transcriptome from the deep-sea hydrothermal vent mussel Bathymodiolus azoricus, BMC Genomics, vol.11, issue.559, 2010.

R. Bettencourt, M. Rodrigues, I. Barros, T. Cerqueira, C. Freitas et al., Site-related differences in gene expression and bacterial densities in the mussel Bathymodiolus azoricus from the Menez Gwen and Lucky Strike deep-sea hydrothermal vent sites, Fish & Shellfish Immunology, vol.39, issue.2, pp.343-53, 2014.
DOI : 10.1016/j.fsi.2014.05.024

V. Bischoff, C. Vignal, B. Duvic, I. G. Boneca, J. A. Hoffmann et al., Downregulation of the Drosophila Immune Response by Peptidoglycan-Recognition Proteins SC1 and SC2, PLoS Pathogens, vol.17, issue.2, pp.139-0147, 2006.
DOI : 10.1371/journal.ppat.0020014.sg002
URL : https://hal.archives-ouvertes.fr/hal-00095084

I. Boutet, R. Ripp, O. Lecompte, C. Dossat, E. Corre et al., Conjugating effects of symbionts and environmental factors on gene expression in deep-sea hydrothermal vent mussels, BMC Genomics, vol.34, issue.Suppl 1, pp.10-1186, 2011.
DOI : 10.1093/bioinformatics/btm412
URL : https://hal.archives-ouvertes.fr/inserm-00642454

C. M. Cavanaugh, C. O. Wirsen, and H. W. Jannasch, Evidence for methylotrophic symbionts in a hydrothermal vent mussel (Bivalvia: Mytilidae) from the Mid-Atlantic Ridge, Appl. Environ. Microbiol, vol.58, pp.3799-3803, 1992.

A. K. Choe, T. Werner, S. Stöven, D. Hultmark, and V. Kathryn, Requirement for a Peptidoglycan Recognition Protein (PGRP) in Relish Activation and Antibacterial Immune Responses in Drosophila, Science, vol.296, issue.5566, pp.359-362, 2002.
DOI : 10.1126/science.1070216

A. Colaço, F. Dehairs, and D. Desbruyères, Nutritional relations of deep-sea hydrothermal fields at the Mid-Atlantic Ridge: a stable isotope approach, Deep Sea Research Part I: Oceanographic Research Papers, vol.49, issue.2, pp.395-412, 2002.
DOI : 10.1016/S0967-0637(01)00060-7

J. E. Cooper, Early interactions between legumes and rhizobia: disclosing complexity in a molecular dialogue, Journal of Applied Microbiology, vol.72, issue.5, pp.1355-1365, 2007.
DOI : 10.1111/j.1365-2672.2007.03366.x

D. L. Distel, H. K. Lee, and C. M. Cavanaugh, Intracellular coexistence of methano- and thioautotrophic bacteria in a hydrothermal vent mussel., Proc. Natl.Acad.Sci. USA 92, pp.9598-9602, 1995.
DOI : 10.1073/pnas.92.21.9598

N. Dubilier, C. Bergin, and C. Lott, Symbiotic diversity in marine animals: the art of harnessing chemosynthesis, Nature Reviews Microbiology, vol.214, issue.10, pp.725-4010, 1038.
DOI : 10.1264/jsme2.22.136

S. Duperron, C. Bergin, F. Zielinski, A. Blazejak, A. Pernthaler et al., A dual symbiosis shared by two mussel species, Bathymodiolus azoricus and Bathymodiolus puteoserpentis (Bivalvia: Mytilidae), from hydrothermal vents along the northern Mid-Atlantic Ridge, Environmental Microbiology, vol.24, issue.8, pp.1441-1447, 2006.
DOI : 10.1128/AEM.69.11.6785-6792.2003
URL : https://hal.archives-ouvertes.fr/hal-00198901

R. Dziarski and D. Gupta, Peptidoglycan recognition proteins (PGRPs), Molecular Immunology, vol.40, issue.12, 2006.
DOI : 10.1016/j.molimm.2003.10.011
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779587

A. Fiala-médioni, Z. P. Mckiness, P. Dando, J. Boulegue, A. Mariotti et al., Ultrastructural, biochemical, and immunological characterization of two populations of the mytilid mussel Bathymodiolus azoricus from the Mid-Atlantic Ridge: evidence for a dual symbiosis, Mar. Biol, vol.141, pp.1035-1043, 2002.

E. Gelius, C. Persson, J. Karlsson, and H. Steiner, A mammalian peptidoglycan recognition protein with N-acetylmuramoyl-l-alanine amidase activity, Biochemical and Biophysical Research Communications, vol.306, issue.4, pp.988-994, 2003.
DOI : 10.1016/S0006-291X(03)01096-9

M. Gerdol and P. Venier, An updated molecular basis for mussel immunity, Fish & Shellfish Immunology, vol.46, issue.1, 2015.
DOI : 10.1016/j.fsi.2015.02.013

R. Guan and R. A. Mariuzza, Peptidoglycan recognition proteins of the innate immune system, Trends in Microbiology, vol.15, issue.3, pp.127-134, 2007.
DOI : 10.1016/j.tim.2007.01.006

S. Halary, V. Riou, F. Gaill, T. Boudier, and S. Duperron, 3D FISH for the quantification of methane- and sulphur-oxidizing endosymbionts in bacteriocytes of the hydrothermal vent mussel Bathymodiolus azoricus, The ISME Journal, vol.34, issue.3, pp.284-92, 2008.
DOI : 10.2307/3593123
URL : https://hal.archives-ouvertes.fr/hal-00325687

N. Itoh and K. G. Takahashi, Distribution of multiple peptidoglycan recognition proteins in the tissues of Pacific oyster, Crassostrea gigas, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, vol.150, issue.4, pp.409-426, 2008.
DOI : 10.1016/j.cbpb.2008.04.011

E. Kádár, R. Bettencourt, V. Costa, R. S. Santos, A. Lobo-da-cunha et al., Experimentally induced endosymbiont loss and re-acquirement in the hydrothermal vent bivalve Bathymodiolus azoricus, J. Exp. Mar. Bio. Ecol, vol.31812, pp.99-110025, 2004.

T. Kaneko, T. Yano, K. Aggarwal, J. Lim, K. Ueda et al., PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan, Nature Immunology, vol.14, issue.7, pp.715-72310, 1038.
DOI : 10.1038/ni1356

M. Kim, M. Byun, and B. Oh, Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster, Nature Immunology, vol.4, issue.8, pp.787-79310, 1038.
DOI : 10.1038/ni952

A. Kyuno, M. Shintaku, Y. Fujita, H. Matsumoto, M. Utsumi et al., Dispersal and differentiation of deep-sea mussels of the genus Bathymodiolus, 2009.

L. Pennec, M. Donval, A. Herry, and A. , Nutritional strategies of the hydrothermal ecosystem bivalves, Progress in Oceanography, vol.24, issue.1-4, pp.71-80, 1990.
DOI : 10.1016/0079-6611(90)90020-3

F. Leulier, C. Parquet, S. Pili-floury, J. Ryu, M. Caroff et al., The Drosophila immune system detects bacteria through specific peptidoglycan recognition, Nature Immunology, vol.4, issue.5, pp.478-48410, 1038.
DOI : 10.1038/ni922
URL : http://infoscience.epfl.ch/record/151734

X. Li, S. Wang, J. Qi, S. F. Echtenkamp, R. Chatterjee et al., Zebrafish Peptidoglycan Recognition Proteins Are Bactericidal Amidases Essential for Defense against Bacterial Infections, Immunity, vol.27, issue.3, pp.518-529, 2007.
DOI : 10.1016/j.immuni.2007.07.020
URL : http://doi.org/10.1016/j.immuni.2007.07.020

J. Lim, M. Kim, H. Kim, T. Yano, Y. Oshima et al., Structural Basis for Preferential Recognition of Diaminopimelic Acid-type Peptidoglycan by a Subset of Peptidoglycan Recognition Proteins, Journal of Biological Chemistry, vol.281, issue.12, pp.8286-95, 2006.
DOI : 10.1074/jbc.M513030200

E. Martins, A. Figueras, B. Novoa, R. S. Santos, R. Moreira et al., Comparative study of immune responses in the deep-sea hydrothermal vent mussel Bathymodiolus azoricus and the shallow-water mussel Mytilus galloprovincialis challenged with Vibrio bacteria, Fish & Shellfish Immunology, vol.40, issue.2, pp.485-99, 2014.
DOI : 10.1016/j.fsi.2014.07.018

P. Mellroth, J. Karlsson, and H. Steiner, A Scavenger Function for a Drosophila Peptidoglycan Recognition Protein, Journal of Biological Chemistry, vol.278, issue.9, pp.7059-7064, 2003.
DOI : 10.1074/jbc.M208900200

T. Michel, J. M. Reichhart, J. A. Hoffmann, and J. Royet, Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein, Nature, vol.414, issue.6865, pp.756-759, 2001.
DOI : 10.1038/414756a

J. Miyazaki, L. De-oliveira-martins, Y. Fujita, H. Matsumoto, and Y. Fujiwara, Evolutionary Process of Deep-Sea Bathymodiolus Mussels, PLoS ONE, vol.5, issue.4, 2010.
DOI : 10.1371/journal.pone.0010363.t002

D. Ni, L. Song, L. Wu, Y. Chang, Y. Yu et al., Molecular cloning and mRNA expression of peptidoglycan recognition protein (PGRP) gene in bay scallop (Argopecten irradians, Lamarck 1819), Developmental & Comparative Immunology, vol.31, issue.6, pp.548-558, 2007.
DOI : 10.1016/j.dci.2006.09.001

S. V. Nyholm, P. Song, J. Dang, C. Bunce, and P. R. Girguis, Expression and Putative Function of Innate Immunity Genes under in situ Conditions in the Symbiotic Hydrothermal Vent Tubeworm Ridgeia piscesae, PLoS ONE, vol.35, issue.6, pp.1-12, 2012.
DOI : 10.1371/journal.pone.0038267.s004

S. Reynolds and J. Rolff, Immune function keeps endosymbionts under control, Journal of Biology, vol.7, issue.8, 2008.
DOI : 10.1186/jbiol88
URL : http://doi.org/10.1186/jbiol88

J. L. Salerno, S. A. Macko, S. J. Hallam, M. Bright, Y. J. Won et al., Characterization of Symbiont Populations in Life-History Stages of Mussels From Chemosynthetic Environments, The Biological Bulletin, vol.208, issue.2, pp.145-155, 2005.
DOI : 10.2307/3593123

E. Fink, D. Breusing, C. Reusch, T. B. Rosenstiel, P. Schilhabel et al., Abundant toxin-related genes in the genomes of beneficial symbionts from deep-sea hydrothermal vent mussels, 2002.

C. Swaminathan, P. Brown, A. Roychowdhury, Q. Wang, R. Guan et al., Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs), Proceedings of the National Academy of Sciences, vol.103, issue.3, pp.684-649, 2006.
DOI : 10.1073/pnas.0507656103
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334652

A. Takehana, T. Yano, S. Mita, A. Kotani, Y. Oshima et al., Peptidoglycan recognition protein (PGRP)-LE and PGRP-LC act synergistically in Drosophila immunity, The EMBO Journal, vol.36, issue.23, 2004.
DOI : 10.1074/jbc.271.23.13854

V. Tunnicliffe, The biology of hydrothermal vents : ecology and evolution. Oceanogr, Mar. Biol. Ann. Rev, vol.29, pp.319-407, 1991.

C. L. Van-dover and B. Fry, Microorganisms as food resources at deep-sea hydrothermal vents, Limnology and Oceanography, vol.39, issue.1, pp.51-57, 1994.
DOI : 10.4319/lo.1994.39.1.0051

Z. M. Wang, X. Li, R. R. Cocklin, M. Wang, M. Wang et al., Human Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L-alanine Amidase, Journal of Biological Chemistry, vol.278, issue.49, pp.49044-49052, 2003.
DOI : 10.1074/jbc.M307758200

B. Webb, M. A. Marti-renom, M. S. Madhusudhan, D. Eramian, M. Shen et al., Comparative protein structure modeling using Modeller, Current protocols in bioinformatics, 2006.

X. Wei, J. Yang, D. Yang, J. Xu, X. Liu et al., Molecular cloning and mRNA expression of two peptidoglycan recognition protein (PGRP) genes from mollusk Solen grandis, Fish & Shellfish Immunology, vol.32, issue.1, pp.178-185, 2012.
DOI : 10.1016/j.fsi.2011.11.009

C. Wentrup, A. Wendeberg, M. Schimak, C. Borowski, and N. Dubilier, Forever competent: deep-sea bivalves are colonized by their chemosynthetic symbionts throughout their lifetime, Environmental Microbiology, vol.12, issue.12, pp.3699-713, 2014.
DOI : 10.1111/1462-2920.12597

T. Werner, G. Liu, D. Kang, S. Ekengren, H. Steiner et al., A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster, Proceedings of the National Academy of Sciences, vol.97, issue.25, pp.13772-13777, 2000.
DOI : 10.1073/pnas.97.25.13772

Y. Won, S. J. Hallam, G. D. O-'mullan, I. L. Pan, K. R. Buck et al., Environmental Acquisition of Thiotrophic Endosymbionts by Deep-Sea Mussels of the Genus Bathymodiolus, Applied and Environmental Microbiology, vol.69, issue.11, pp.6785-6792, 2003.
DOI : 10.1128/AEM.69.11.6785-6792.2003

Y. H. Wong, J. Sun, L. S. He, L. G. Chen, J. Qiu et al., High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons, Scientific Reports, vol.17, 2015.
DOI : 10.1038/srep16597

H. Yoshida, K. Kinoshita, and M. Ashida, Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori, J. Biol. Chem, vol.271, 1996.